The draft genome of the large yellow croaker reveals well-developed innate immunity

نویسندگان

  • Changwen Wu
  • Di Zhang
  • Mengyuan Kan
  • Zhengmin Lv
  • Aiyi Zhu
  • Yongquan Su
  • Daizhan Zhou
  • Jianshe Zhang
  • Zhou Zhang
  • Meiying Xu
  • Lihua Jiang
  • Baoying Guo
  • Ting Wang
  • Changfeng Chi
  • Yong Mao
  • Jiajian Zhou
  • Xinxiu Yu
  • Hailing Wang
  • Xiaoling Weng
  • Jason Gang Jin
  • Junyi Ye
  • Lin He
  • Yun Liu
چکیده

The large yellow croaker, Larimichthys crocea, is one of the most economically important marine fish species endemic to China. Its wild stocks have severely suffered from overfishing, and the aquacultured species are vulnerable to various marine pathogens. Here we report the creation of a draft genome of a wild large yellow croaker using a whole-genome sequencing strategy. We estimate the genome size to be 728 Mb with 19,362 protein-coding genes. Phylogenetic analysis shows that the stickleback is most closely related to the large yellow croaker. Rapidly evolving genes under positive selection are significantly enriched in pathways related to innate immunity. We also confirm the existence of several genes and identify the expansion of gene families that are important for innate immunity. Our results may reflect a well-developed innate immune system in the large yellow croaker, which could aid in the development of wild resource preservation and mariculture strategies.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2014